2010 Green Bay Packers Schedule
Pre-Season
| Date | Opponent | Time |
| Saturday, August 14th | at Cleveland Browns | 7:00 p.m. |
| Saturday, August 21st | at Seattle Seahawks | 9:00 p.m. |
| Thursday, August 26th | Indianapolis Colts | 7:00 p.m. |
| Thursday, September 2nd | at Kansas City Chiefs | 7:00 p.m. |
Regular Season
| Date | Opponent | Time |
| Sunday, September 12th | at Philadelphia Eagles | 3:15 p.m |
| Sunday, September 19th | Buffalo Bills | 12:00 p.m. |
| Monday, September 27th | at Chicago Bears | 7:30 p.m. |
| Sunday, October 3rd | Detroit Lions | 12:00 p.m. |
| Sunday, October 10th | at Washington Redskins | 12:00 p.m. |
| Sunday, October 17th | Miami Dolphins | 12:00 p.m. |
| Sunday, October 24th | Minnesota Vikings | 7:20 p.m. |
| Sunday, October 31st | at New York Jets | 12:00 p.m. |
| Sunday, November 7th | Dallas Cowboys | 7:20 p.m. |
| Sunday, November 14th | By-Week | |
| Sunday, November 21st | at Minnesota Vikings | 12:00 p.m. |
| Sunday, November 28th | at Atlanta Falcons | 12:00 p.m. |
| Sunday, December 5th | San Francisco 49ers | 12:00 p.m. |
| Sunday, December 12th | at Detroit Lions | 12:00 p.m. |
| Sunday, December 19th | at New England Patriots | 7:20 p.m. |
| Sunday, December 26th | New York Giants | 3:15 p.m. |
| Sunday, January 2nd | Chicago Bears | 12:00 p.m. |